South East Asia Journal of Medical Sciences <div id="journalDescription"> <div id="journalDescription"> <div id="journalDescription"> <div id="coverJOSI"><img style="/* width: 5%; */float: left; width: 119px; margin-right: 1.2em; text-align: left;" src="" alt="SEAJMS" /></div> <div> <p style="background-color: #fffdf7; padding: 5px 10px; border-bottom: 3px solid #ffba39; font-size: 0.9em;"><strong>Title:</strong> South East Asia Journal of Medical Sciences<br /><strong>ISSN:</strong> <a href="" target="_blank" rel="noopener">2522-7165</a> (online), <a href="" target="_blank" rel="noopener">2520-7342</a> (print)<br /><strong>Indexed at: </strong><a href="" target="_blank" rel="noopener">ROAD</a>, <a href=";type=all&amp;oaboost=1&amp;ling=1&amp;name=&amp;thes=&amp;refid=dcresen&amp;newsearch=1" target="_blank" rel="noopener">Base</a>, <a href="" target="_blank" rel="noopener">PKP Index</a>, <a href=";qt=results_page" target="_blank" rel="noopener">OCLC WorldCat</a><br /><strong>Citation:</strong> <a href=";as_sdt=0%2C5&amp;;oq=" target="_blank" rel="noopener">Google Scholar</a><br /><strong>Archive Preservation:</strong> <a href="" target="_blank" rel="noopener">The Keepers (PKP PN)</a><br /><strong>OAI:</strong> <a href="" target="_blank" rel="noopener"></a></p> </div> </div> </div> </div> Little Bay Publishers en-US South East Asia Journal of Medical Sciences 2520-7342 <p>The authors agreed following terms while submitting the article:</p> <ol type="a"> <ol type="a"> <li>I and coauthors retain copyright and grant the journal right of first publication with the work and also agree that, if accepted by the editorial team, shall be licensed under a <a href="" rel="license">Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License</a> (Articles can be shared and adapted, provided the attribution for the work is given and that the work is not used for commercial purposes), full details of which can be found <a href="">here.</a></li> <li>I, on behalf of myself and my co-authors, authorize that: <ul> <li>​​the article is original and was not published in any other peer-reviewed journal, and is not under consideration by any other journal, and does not violate any existing copyright or any other third party rights.</li> </ul> </li> </ol> </ol> Differential diagnosis of benign ovarian cysts using tumor markers in serum and cyst fluid <p><strong>Background: </strong>Differentiating the type of benign ovarian cyst can result in better care.</p> <p><strong>Aims: </strong>To measure CA-125, CA 19-9, Carcinoembryonic Antigen (CEA) and Alpha-fetoprotein (AFP) in serum and cyst fluid of patients with benign ovarian cysts and whether these biomarkers can be used to identify the type of the cyst.</p> <p><strong>Methods and materials:</strong> Patients with benign ovarian cysts undergoing laparoscopic cystectomy were included. Cyst types were determined histologically. Levels of CA 125, CA 19-9, CEA and AFP were measured in serum and cyst fluid.</p> <p><strong>Results: </strong>98 cysts (25 functional, 12 endometrioma, 15 dermoid, 28 mucinous cystadenoma, 18 serous cystadenoma) were evaluated. There was a significant difference in levels of CA 125 and CA 19-9 in serum and CA-125, CA 19-9 and CEA in cyst fluid. For diagnostic purposes, a value of ≥35 IU/mL for serum CA 125 predicted endometriomas with a sensitivity of 91.7% and a specificity of 91.9%. A value of ≤22.5 IU/mL for cyst fluid CA 19-9, predicted functional cysts with a of sensitivity of 92% and specificity of 95.2%. A value of ≥100 ng/mL for cyst fluid CEA, predicted mucinous cysts with a sensitivity of 96.4% and specificity of 96.7%.</p> <p><strong>Conclusion:</strong> Levels of CA-125, CA 19-9 and CEA in serum and cyst fluid of patients with benign ovarian cysts can be used as a diagnostic tool in patient evaluation with acceptable sensitivity and specificity. This finding can be used in conjunction with other methods such as ultrasound, especially in cases that are harder to diagnose.</p> Leila Yaminifar Soroush Dianaty Zohreh Shahverdi Mansooreh Yaraghi Batool Ghorbani Yekta Copyright (c) 2021 Leila Yaminifar, Soroush Dianaty, Zohreh Shahverdi, Mansooreh Yaraghi, Batool Ghorbani Yekta 2021-09-08 2021-09-08 1 7 Evaluation of Changes in Maternal Blood Sugar and Renal Function Tests during Gestational Period <p><strong>Background and Objectives</strong></p> <p>The direct effects of altered maternal glucose metabolism and renal impairment from early pregnancy onwards with complications on mother as well as fetal growth and the risks of adverse birth outcomes. It is crucial to understand the biochemical changes to appropriately interpret common laboratory tests for evaluating renal disease and hyperglycemia in women during pregnancy. Thus, the study was focused to estimate the variability in blood glucose and renal functions as well as its association with BMI during pregnancy in Southern Terai of Province No. 2, Nepal.</p> <p><strong>Materials and Methods</strong></p> <p>Fasting blood glucose was determined by enzymatic (GOD/POD) method, Serum Urea by Urease-Bertholet’s Method, Serum creatinine by Jaffe’s Reaction Method, and Uric acid by Uricase method. All the biochemical parameters were analyzed using semi-automatic biochemical analyzer (Humalyzer 3500). Statistical analysis of the collected data was carried out using SPSS version 20. The p-value &lt; 0.05 was considered statistically significant.</p> <p><strong>Results </strong></p> <p>The mean with standard deviation for fasting blood glucose (94.01<u>+</u>30.88; 99.71<u>+</u>23.97; 104.77<u>+</u>21.37) urea (23.22<u>+</u>7.89; 18.22<u>+</u>8.98; 20.64<u>+</u>9.09), creatinine (0.68<u>+</u>0.24; 0.65<u>+</u>0.20; 0.58<u>+</u>0.28), uric acid level with (3.14<u>+</u>0.93, 3.74<u>+</u>0.95, 3.95<u>+</u>0.85) was depicted in 1<sup>st</sup>, 2<sup>nd</sup> and 3<sup>rd</sup> trimester of pregnancy. Glucose and BMI were positively correlated and highly significant (r=0.191; p&lt;0.01). BMI with urea was negatively correlated and was found to be highly significant(r= -0.196; p&lt;0.01). Also, there was a negative correlation between BMI and Creatinine and was found to be significant (r=-0.132; p&lt;0.01). But, the association of uric acid was positively correlated and statistically insignificant.</p> <p><strong>Conclusion</strong></p> <p>Blood glucose and uric acid gradually start increasing trimester-wise with the advancement of the gestational period. But, the mean urea level was decreased in the 2<sup>nd</sup> trimester as compared to the 1<sup>st</sup> and 3<sup>rd</sup> trimester. Also, small variation for creatinine level was found in different trimesters of pregnancy. </p> <p>The association of Glucose, uric acid, and BMI were positively correlated and statistically insignificant whereas Urea and BMI was negatively correlated and highly significant. Also, there was a negative correlation between BMI and Creatinine and was found to be significant.</p> Satyam Prakash Dipendra Raj Pandeya Jitendra Kumar Singh Khushbu Yadav Basant Kumar Yadav Copyright (c) 2021 Satyam Prakash, Dipendra Raj Pandeya, Jitendra Kumar Singh, Khushbu Yadav, Basant Kumar Yadav 2021-05-08 2021-05-08 1 8 10.5281/zenodo.4840603 Stress and menstrual disorders among Iranian medical students: A cross-sectional study Background: Menstrual disorders are common among women and can cause discomfort. Several environmental factors are considered to be associated with these disorders. Aim: To investigate the prevalence of psychological stress and menstrual disorders among Iranian medical students and to assess the environmental factors, including stress, that are associated with menstrual disorders. Methods and material: This cross-sectional study was conducted on female medical students of Islamic Azad University Tehran Medical Sciences Branch, Tehran, Iran. Demographics, menstrual patterns and stress profile of the sample were assessed. Logistic regression models were used to evaluate factors associated with stress and menstrual disorders. Results: Out of 358 participants, 10.1% had a menstrual cycle < 21 days (polymenorrhea), 2.8% had a menstrual cycle of >35 days (oligomenorrhea), and 9.2% had irregular menstrual cycle (metrorrhagia). Moreover, 13.7% had period lengths of >7 days (hypermenorrhea). 51.1% of the sample experienced heavy menstrual bleeding (menorrhagia). The average stress score was 19.87±9.09. BMI, cigarette and hookah smoking were significantly associated with higher stress (OR=1.158, 1.123 and 1.117, respectively). Polymenorrhea was significantly associated with age at menarche and stress score (OR=0.735 and 1.046, respectively). Metrorrhagia was also significantly associated with age at menarche and stress score (OR=0.757 and 1.043, respectively). New interns were less likely to have hypermenorrhea and metrorrhagia compared to pre-interns (OR=0.173 and 0.500, respectively). Conclusions: Stress was associated with short and irregular menstrual cycles. There was a higher prevalence of stress and menstrual disorders among medical students compared to general population, which warrants further investigation and action. Roksana Darabi Behnaz Ghoreshi Soroush Dianaty Maryam Sadat Motevalli Copyright (c) 2021 Roksana Darabi, Behnaz Ghoreshi, Soroush Dianaty, Maryam Sadat Motevalli 2021-09-08 2021-09-08 8 15 ADVERSE SKIN REACTIONS OF PERSONAL PROTECTIVE EQUIPMENT ON HEALTH CARE WORKERS AGAINST COVID -19 <p>The coronavirus outbreak, which was first detected in China, has infected people in 185 countries. COVID-19 is a pneumonia-like disease caused by a new coronavirus, named SARS-CoV-2, that is similar to the virus that causes Severe Acute Respiratory Syndrome (SARS Coronavirus disease 2019 (COVID-19). To study the prevalence of adverse reactions of wearing PPE among healthcare workers in Karnataka India during the Covid -19 outbreak. Twenty-one-day observation were made on twenty laboratory health workers and observed hazardous skin effect on health workers wearing PPE long hours during working period. long hour wearing of PPE in our study found respiratory complications, sweating and skin damage. Adequate dermatological knowledge of PPE use and design and extensive comprehensive training is important in risk of pandemic outbreak.</p> Santosh M. Soraganvi Revanshiddayya S Hiremath Panchaksharayya S Hiremath Manjunath D. Marad Eknath P Jadhav Gavishiddappa A Hadimani Copyright (c) 2020 Santosh M. Soraganvi, Revanshiddayya S Hiremath, Panchaksharayya S Hiremath, Manjunath D. Marad, Eknath P Jadhav, Gavishiddappa A Hadimani 2020-10-25 2020-10-25 16 19 10.5281/zenodo.4584515 Transoral microscopic approach to epidermoid cyst in submandibular space <p>Dermoid cysts are developmental anomalies that arise due to defect in the fusion of embryonic lateral mesenchymal approaches during fifth week of embryonic development. Dermoid cysts can be further subdivided into epidermoid , dermoid and teratoid cysts based on the lining epithelium and contents .We present an unusual case of 32 year old female who presented with a swelling in submandibular space, for whom an initial differential diagnosis of plunging ranula was made. The patient underwent an intraoral microscopic excision of tumor under GA following cytology and radiological investigations .Here we would like to stress the importance of multidisciplinary approach to the disease inorder to confirm the diagnosis, considering the manifold differentials and plan surgical approach. Furthermore, the benefits of undergoing an intra oral microscopic excision of the tumor, as it provides better cosmesis , functional outcome and reduced hospital stay.</p> Abhishek Bhardwaj Areej Moideen Arya V Manu Malhotra Madhu priya Saurabh Varshney Joyson Antony Xavier Copyright (c) 2020 Abhishek Bhardwaj, Areej Moideen, Arya V, Manu Malhotra, Madhu priya, Saurabh Varshney 2020-10-25 2020-10-25 23 26 10.5281/zenodo.4584503